It's busy at Daantje's father's animal clinic. Amidst all the sick and injured animals, the vet is looking for an assistant, and an extension is being built with new cages for animals that need to stay overnight. Daantje tries to stay out of her father's way as little as possible, but that's quite difficult when there's absolutely nothing to look for! Fortunately, an animal ambulance has recently arrived in the area that works closely with Daantje's father, and Daantje and her best friend Tofu regularly get to go out with the kind driver Karel. For example, they rescue a hedgehog from a dire situation and rescue an injured cat from a roof.
When that cat is then stolen from the clinic, Daantje, Tofu, and Pluis immediately launch an investigation. Will they manage to find the culprit?